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Guideline-directed medical therapy (GDMT) implementation in patients with heart failure and chronic kidney disease

Cardiology
Curriculum:
Optimizing Heart Failure Management: A High-Intensity, Patient-Centered Approach to Guideline-Directed Medical Therapy
Launch Date:
August 12, 2025
Expiration Date:
The accreditation for this activity has expired.

Primary Audience:

Cardiologists, emergency medicine, critical care, and primary care physicians, in addition to other healthcare professionals involved in the diagnosis, management, and treatment of patients with heart failure.

Relevant Terms:

Guideline-directed medical therapy; guidelines; heart failure (HF); heart failure with reduced ejection fraction (HFrEF); heart failure with preserved ejection fraction (HFpEF); therapy; medications; implementation; treatment initiation; treatment uptitration

Gianluigi Savarese, MD, PhD, FESC, FHFA

Professor of Cardiology and Senior Lecturer
Head of the Heart Failure and Arrhythmia Research Group
Department of Clinical Science and Education
Karolinska Institutet, Stockholm, Sweden

Senior Consultant for Heart failure 
Southern Hospital, Stockholm, Sweden

Gianluigi Savarese is an Italian/Swedish cardiologist, currently Professor of Cardiology and Senior Lecturer at Karolinska Institutet (Department of Clinical Science and Education) where he is head of the Center for Heart Failure and Arrhythmia. He is also Senior Consultant for Heart Failure at the Southern Hospital, Stockholm, Sweden. Over the last few years, he has published >300 articles in top peer-reviewed journals. The major focus of his research is heart failure, with a particular interest in implementing use of guideline-recommended treatments, and phenotyping heart failure for improving clinical trial design. He is heavily involved in registry studies (Swedish Heart Failure Registry, ESC registries) and clinical trials, and he is expert in meta-analysis and big data analysis. He is Secretary of the Heart Failure Association, and he has served as board member and secretary of the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology. Among others, he is Deputy Editor of EHJ-Open, EHJ-CR, and Associate Editor of European Journal of Heart Failure.

James O. Burton, DM, FRCP, FHEA

Professor 
University Hospitals of Leicester; UK

James Burton is Honorary Consultant Nephrologist, Professor of Renal Medicine and Associate Dean for Clinical Research at the University of Leicester, in the UK. His principal research interests are the mechanisms underlying uremic cardiovascular disease modification of cardiovascular risk in patients with end-stage renal disease and the identification and application of novel biomarkers. In addition, Prof Burton is involved in the development and running of clinical trials; he is Chief Investigator for the NIHR funded NightLife trial investigating the impact of nocturnal dialysis on patient outcomes, as well as the Kidney Research UK funded CONFIRM study exploring the utility of a novel cardiac magnetic resonance imaging (MRI) technique in hemodialysis patients. Prof Burton is the independent Chair of two multi-center NIHR Trial Steering Committees and sits on a number of others. He is the current Chair of the UK Kidney Association Clinical Guidelines Committee and has himself chaired a number of UK guideline updates making sure that research translates into clinical practice.
1. Apply best practices for the assessment and implementation of GDMT in patients with heart failure and chronic kidney disease.

This activity has been accredited by the European Board for Accreditation of Continuing Education for Health Professionals (EBAC®).
 
Through an agreement between the European Board for Accreditation of Continuing Education for Health Professionals and the American Medical Association physicians may convert EBAC® CE credits to AMA PRA Category 1 Credits. Information on the process to convert EBAC credit to AMA credit can be found on the AMA website. Other health care professionals may obtain from the AMA a certificate of having participated in an activity eligible for conversion of credit to AMA PRA Category 1 Credit.

To receive your CME certificate please complete the online evaluation, accessible via QR code, at the end of the activity.
 

COURSE VIEWING REQUIREMENTS

Supported Browsers:
Microsoft Edge
Google Chrome 60 or higher
Mozilla Firefox 60 or higher
Apple Safari 11.0 or higher
For video, install the latest version of Quicktime.
Supported Phones & Tablets:
iOS 9.3 and higher
Android 7.0 (Nougat or higher)
Microsoft Windows 8
Chrome OS

 
Additional Recommendations and Requirements
Display Resolution & Color Depth Resolution
- 960 X 768 minimum
- 1024 X 768 recommended min.

Color Depth
- 8 bits (256 colors) minimum
- 16 bits (High colors) minimum
Audio - Microphone
- Speakers or headphones
- Audio recording support
Word Processing Software that can open, modify, and save documents in Rich Text Format (RTF). Microsoft Word and PowerPoint are recommended.